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Comparison of noise reducing and signal transducing performance of the best performing FFL motifs.

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posted on 03.12.2021, 18:22 by Suchana Chakravarty, Attila Csikász-Nagy

The best performing simple and combined FFL networks are plotted in (A). The corresponding panels with similar layout (B-J) show the performance of each of these networks for the input change presented in Fig 1F. The mean of the output active forms of Z molecules of panel A are plotted with solid blue lines, ± standard deviation is plotted with shading, and coefficient of variation in percentage (% CV) values and slopes of input-output relation curves are labeled on all plots. All simulations were run with one-step post-translational modification models and the fixed parameter sets presented in the S1 Text.

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