Comparing <i>C</i>. <i>muridarum</i> recoveries from vaginal swabs of mice with or without deficiency in STING following a transcervical inoculation.

<p>Groups of C57BL/6J (solid bar or, solid square, n = 10) and STING-deficient (open bar or open square, n = 10) female mice were each inoculated with 2 x 10⁵ IFUs transcervically and at various times after the inoculation as indicated along the X-axis, vaginal swabs were taken for titrating infectious organisms as displayed in Log10 IFUs (left) or % of mice with positive IFU (right) along the Y-Axis. Please note that there is no significant difference in either log10 IFUs (Wilcoxon) or % of mice with positive IFUs (Fisher’s Exact) between the wild type and STING-deficient mice (data obtained from two independent experiments), indicating that the STING-deficiency did not affect the descending of the <i>C</i>. <i>muridarum</i> organisms from the endocervcal compartments into the ectocervical and vaginal compartments or the replication of the <i>C</i>. <i>muridarum</i> organisms in these compartments.</p>