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Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in -3

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posted on 31.12.2011, 03:23 by Tobias Fromme, Kathrin Reichwald, Matthias Platzer, Xing-Sheng Li, Martin Klingenspor

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Taken from "Chicken ovalbumin upstream promoter transcription factor II regulates uncoupling protein 3 gene transcription in "

BMC Molecular Biology 2007;8():1-1.

Published online 4 Jan 2007

PMCID:PMC1779797.

fold change relative to basal -2244luc level). Coup-TFII coactivates the promoter in all combinations. It is especially effective together with MyoD, RXRα and p300. Coup-TFI does not activate reporter gene expression demonstrating a specific effect of Coup-TFII. () Identification of the region mediating Coup-TFII transctivation by analysis of deletion reporter gene constructs. Shown in the upper panel is the basal activity and induction by Coup-TFII of all constructs, in the lower panel the experiment was repeated on a background of MyoD, RXRα and p300 (note the different axis scaling). The shaded area highlights the region that is exclusively found on -2244luc and is responsible for the Coup-TFII effect in both setups.

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