Cell viability (MTT) assay for four conditions - media control, IL-1
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posted on 2025-03-06, 18:23 authored by Anna Cordeiro-Santanach, Fiorella Morales, Maria del Carmen Parquet, Kitipong Uaesoontrachoon, Joyce Rowsell, Jordan Warford, Wilson Wu, Pia Elustondo, Eric P. Hoffman, Kanneboyina Nagarajuβ 10 ng/ml, Canakinumab 10 nM, and the co-incubation of IL-1β 10 ng/ml and canakinumab 10 nM after 72 hrs of treatment (n = 2 biological replicates, n = 3 technical replicates). Data shown as mean ± SEM.
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mdx mouse modellinked immunosorbent assayduchenne muscular dystrophy264 &# 8201126 &# 8201unlike previous generationsaffect myotube viabilityactivated inflammatory pathwayspreviously published prediv >< p10 &# 82011 &# 946significantly reduced il1000 nm relativeskeletal muscle cellsviability assayssignificantly reduceprevious methodinflammatory cytokines1000 nmmuscle inflammationmuscle cellstreat dmdtherapeutic repositioningtaken togetherspecifically blockssignificant inhibitionresults showresults alignpotent inhibitormyokine interleukinilaris ®))highly specificexcellent candidatedmd ).clinical workclinical utilityassess toxicityapproved drugalso able48 hours1 inhibitors001 nm
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