CD40fl/flLysMcre mice have similar glucose tolerance and insulin resistance than their WT controls.
figureposted on 10.08.2018, 17:39 by Suzanne A. B. M. Aarts, Myrthe E. Reiche, Myrthe den Toom, Linda Beckers, Marion J. J. Gijbels, Norbert Gerdes, Menno P. J. de Winther, Esther Lutgens
(A) Glucose tolerance test (n = 6–9 mice/group). (B) Insulin tolerance test (n = 6–16 mice/group). (C) Fasted glucose levels (n = 6–9 mice/group). (D) Fasted insulin levels (n = 5–8 mice/group). Data is presented as mean ± SEM.
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adipose tissue leukocyte infiltrationWT40LMacrophage CD 40SFDadipose tissue inflammation40-CDameliorates adipose tissue inflammationinsulin resistanceHFDCD 40 flfl LysM creincreases insulin sensitivitymacrophage CD 40adipose tissue weightDIOplasma adiponectin levelstriglyceride levelsmacrophage CD 40. CD 40 flfl LysM cre miceadipose tissue cytokine levels