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Breast cancer summary heatmap.

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posted on 2024-03-21, 19:39 authored by Marta Lovino, Elisa Ficarra, Loredana Martignetti

The heatmap reports in red the miRNA-genes pairs resulting significantly with the MoPC analysis. In dark green, the miRNA-genes pairs are statistically significant in the input dataset and validated in at least one of the three databases (miRDB, TargetScan, and miRTarBase). Genes are reported on the rows, and miRNAs on the columns. Both genes and miRNAs are chromosomally ordered. Only the 5p’ most expressed miRNAs in breast cancer, according to isomiRTar [6], have been reported in the columns to provide more understandable results.

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