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Brca1 expression in the mouse mammary gland

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posted on 2011-12-30, 14:05 authored by Christopher R Mueller, Calvin D Roskelley

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Taken from "Regulation of expression and its relationship to sporadic breast cancer"

Breast Cancer Research 2002;5(1):45-52.

Published online 13 Nov 2002

PMCID:PMC154136.

Copyright © 2003 BioMed Central Ltd

The line represents relative brca1 expression levels and is regulated in periodic waves during mammary gland development. Levels are low in the quiescent periods before puberty, in the virgin adult gland and in the resting gland. Levels are also low during lactational terminal differentiation. Levels are high during the proliferative periods at puberty and during pregnancy. Levels are also high during the apoptotic period of involution after weaning.

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