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Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model - Fig 11

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posted on 2017-04-28, 17:43 authored by Jing Luo, Biying Dong, Ke Wang, Shuangqi Cai, Tangjuan Liu, Xiaojing Cheng, Danqing Lei, Yanling Chen, Yanan Li, Jinliang Kong, Yiqiang Chen

Comparison of Gross (A) and Microscopic (B) Pathological Changes in the Peritoneal Tissue after Treatment with Vehicle or Baicalin. Histopathology was performed using an upright microscope at 200× magnification. The white arrow indicates the implant.

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Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model
PLOS ONEPLOS ONE

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Pseudomonas aeruginosa pathogenicitysub-MIC baicalin treatmentGreater worm survivalquorum sensing-controlled virulence4-HSLmolecules 3- oxo-C 12-HSLcontrol groupQS-controlled biofilm formationbiofilm formationIFNbaicalin treatment groupPseudomonas aeruginosa biofilmsbaicalin-mediated QS inhibitionimplant infection modelPseudomonas aeruginosa biofilm-related infectionsLTILPseudomonas aeruginosaPseudomonas aeruginosa clearancebaicalin treatment

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