pone.0264398.g005.tif (2.17 MB)
BP-target-pathway network and PPI network of top 10 hub genes for SHCZF against cholestasis.
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posted on 2022-02-23, 18:30 authored by Binbin Liu, Jie Zhang, Lu Shao, Jiaming Yao(A) The BP-target-pathway network included 83 potential targets (flesh-colored circles), top 15 BP terms (purple circles), and top 15 KEGG pathways (green circles). (B) PPI network of top 10 hub targets (ALB, IL6, AKT1, TP53, TNF, MAPK3, APOE, IL1B, PPARG, and PPARA) for SHCZF against cholestasis.
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performance liquid chromatographygood binding affinitygenomes enrichment analysisfluid shear stressrage signaling pathwaynetwork pharmacology analysismajor chemical compoundscritical hub targetsmolecular docking showedhub target proteins141 bioactive compounds83 potential targetscholestasis mainly involvedpathway networkmolecular dockingmainly involvedbioactive compoundsbiological compoundsrelated targetspotential targetsintersected targetszhu formulaxlink ">venn diagramtarget networksstudy predictedstudy aimedstring databasepublic databaseskyoto encyclopediagene ontologydrug metabolismdiabetic complicationscytochrome p450cholestasis treatmentbiological functions
