BOLD/CBF coupling.

(A) Group averaged correlation between CBF and BOLD time-series for non-denoised (PW,E2) and denoised (PWDN,MECDN) data for SS (left) and HD data (right). In general, CBF-BOLD correlation increased with denoising. This was confirmed quantitatively (B) where the mean correlation extracted from a mask of significantly correlated voxels was highest for fully denoised datasets (PWDN,MECDN). *** = p<0.001, ** = p<0.01, * = p<0.05, Bonferroni-corrected.