Aspirate smear of five cases of BI-ALCL.
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posted on 2017-07-17, 17:46 authored by Arianna Di Napoli, Giuseppina Pepe, Enrico Giarnieri, Claudia Cippitelli, Adriana Bonifacino, Mauro Mattei, Maurizio Martelli, Carlo Falasca, Maria Christina Cox, Iolanda Santino, Maria Rosaria GiovagnoliA. Case 1. B. Case 2. C. Relapse of case 2. D. Case 3. E. Case 4. F. Case 5. Smears showed large to medium-size atypical cells with irregularly shaped nuclei, conspicuous nucleoli and abundant clear cytoplasm in a fibrinous background. Morphologic features of BI-ALCL included hallmark cells with kidney-shaped nuclei (A arrows), binucleated Reed-Stenberg-like cells (B and E), cells with multiple nuclei (D) and mononucleated cells with prominent single or multiple nucleoli (D, E, F) (Papanicolaou smear, original magnification x400).
