pone.0242321.g001.tif (1.38 MB)

Analysis of metabolomic alterations of the PML and control samples.

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posted on 24.11.2020, 18:23 by Yi Luo, Nora Möhn, Amani Al-Mekhlafi, Sven Schuchardt, Thomas Skripuletz, Wolfram Sühs, Frank Pessler, Martin Stangel

(A) Partial least squares discriminant analysis (PLS-DA) scores plot showing some separation between the PML (n = 23) and NPH (n = 8) subjects based on their metabolic profile of selected metabolites. (B) Concentrations of the 19 most promising metabolites (VIP>1). (C) Areas under the receiver-operating characteristic curves (AUROCs) of combinations of metabolites. (D) Variable influence on projection (VIP) plot showing the metabolites that are most important in driving the separation of the two groups.