Analysis of VE-Cadherin borders of EC exposed to liver cirrhosis patients.

<p><b>A:</b> PCA plot of the VE-cadherin cluster profiles of ECs exposed to patient derived plasmas or healthy control plasmas. Plotted are the first and third PC, both containing information about the disease severity, explaining 79% of variance combined. <b>B:</b> Heatmap showing the cosine similarity between patient profiles and the VE-Cadherin morphologies induced by EC stimulants. Color corresponds to cosine similarity score with the red color indicating high, and the blue color indicating low similarity. <b>C:</b> Examples of cell morphology for ECs exposed to plasma from either healthy controls, compensated liver cirrhosis patients, or decompensated liver cirrhosis patients. ECs of decompensated group are more highly activated compared to healthy controls.</p>