pone.0221340.g004.tif (343.7 kB)

Analysis of ROC curves for the two DCE perfusion parameters, Ktrans and Kep, in the discrimination between low and high HIF-1α expression.

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posted on 22.08.2019 by Auni Lindgren, Maarit Anttila, Suvi Rautiainen, Otso Arponen, Kirsi Hämäläinen, Mervi Könönen, Ritva Vanninen, Hanna Sallinen

The analysis reveals the diagnostic accuracy of A) Ktrans L-ROI (AUC = 0.832) B) Ktrans S-ROI (AUC = 0.840), C) Kep L-ROI (AUC = 0.808) and D) Kep S-ROI (AUC = 0.808). HIF-1α expression dichotomized into low and high using the median immunoreactive score as the cutoff value.