pone.0200211.g005.tif (573.06 kB)

Alternative splicing of helicase-like transcription factor (Hltf): Intron retention-dependent activation of immune tolerance at the feto-maternal interface - Fig 5

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posted on 2018-07-05, 17:53 authored by Gurvinder Kaur, Rebecca A. Helmer, Lisa A. Smith, Raul Martinez-Zaguilan, Jannette M. Dufour, Beverly S. Chilton

Gene measured composite volcano and expression bar plots: A. Volcano plot highlighting increased expression of perforin 1 (Prf1) and granzyme B (Gzmb) when Hltf is deleted. B. All the differentially increased genes [perforin1 (Prf1), albumin (Alb), fibrinogen-like protein 2 (Fgl2), granzymes (Gzmb-Grzmg) and lysozyme 2 (Lyz2)] that are annotated to cytolysis are ranked based on the significance of their measured logFC. The box and whisker plot on the left summarizes the distribution of all the differentially increased genes that are annotated to this GO:0019835 term. The box represents the 1st quartile, the median and the 3rd quartile.