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Allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma-0

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posted on 31.12.2011 by Michael G Anderson, K Saidas Nair, Leslie A Amonoo, Adrienne Mehalow, Colleen M Trantow, Sharmila Masli, Simon WM John
S to the D2 form of glaucoma, is expressed in BM derived cells. Agarose gel of designated RT-PCR products amplified from iris (I), bone marrow (BM), lymph node (L), or thymus (T) of normal C57BL/6J mice. () Iris lysates from D2 and D2-mice were analyzed on Western blot with anti-GPNMB antibody (B). There is no protein of the expected size for GPNMB (arrow) in the D2 lysate. The faint bands of lower molecular weight likely represent background cross-reactivity of the antibody.

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Taken from "allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma"

http://www.biomedcentral.com/1471-2156/9/30

BMC Genetics 2008;9():30-30.

Published online 10 Apr 2008

PMCID:PMC2373794.

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