13287_2020_1615_MOESM4_ESM.jpg (3.81 MB)
Download fileAdditional file 4 of Tumor necrosis factor α in aGVHD patients contributed to the impairment of recipient bone marrow MSC stemness and deficiency of their hematopoiesis-promotion capacity
figure
posted on 2020-03-18, 04:46 authored by Li Ding, Hong-Mei Ning, Pei-Lin Li, Hong-Min Yan, Dong-Mei Han, Xiao-Li Zheng, Jing Liu, Ling Zhu, Mei Xue, Ning Mao, Zi-Kuan Guo, Heng Zhu, Heng-Xiang WangAdditional file 4: Figure S4. TNF-α changed the mRNA expression profile of human BM MSCs. (A) The expression of pathway in human BM MSCs after primed by TNF-α(n = 3). (B) The gene changes were validated by Q-PCR. **, p < 0.01, compared with no TNF-α groups, n = 5.
Funding
National Natural Sciences Grants China
History
References
- 10.1182/blood-2017-09-772673
- 10.1038/nrrheum.2017.7
- 10.1038/nri3212
- 10.1182/blood-2014-02-514745
- 10.1182/blood-2009-11-253559
- 10.1002/stem.1691
- 10.1182/blood-2013-11-539031
- 10.3389/fimmu.2016.00118
- 10.1371/journal.pone.0104607
- 10.1038/nprot.2009.238
- 10.1038/nature09262
- 10.1038/nature12984
- 10.1038/ncb3530
- 10.1016/j.stem.2017.07.004
- 10.1038/s41580-019-0103-9
- 10.3109/10428194.2013.858815
- 10.1182/blood-2009-03-208983
- 10.1016/j.bbmt.2015.01.014
- 10.1016/j.bbmt.2015.02.013
- 10.1038/bmt.2015.189
- 10.1038/nature02040
- 10.1016/j.cell.2019.04.040
- 10.1038/ncb3570
- 10.1038/nature08099
- 10.1038/leu.2014.151
- 10.1038/sj.leu.2402151
- 10.1038/sj.leu.2402946
- 10.1182/blood-2016-04-711275
- 10.3389/fimmu.2019.02040
- 10.1016/j.exphem.2012.07.011
- 10.1056/NEJM199707173370301
- 10.1016/S0145-2126(02)00082-6
- 10.1089/jir.2011.0120
- 10.1089/ten.tea.2014.0007
- 10.1002/sctm.19-0300
- 10.1186/s13287-017-0607-1
- 10.1155/2014/508216