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Additional file 4: Figure S4. of Are minor alleles more likely to be risk alleles?

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posted on 19.01.2018, 05:00 authored by Takashi Kido, Weronika Sikora-Wohlfeld, Minae Kawashima, Shinichi Kikuchi, Naoyuki Kamatani, Anil Patwardhan, Richard Chen, Marina Sirota, Keiichi Kodama, Dexter Hadley, Atul Butte
Log-transformed P-values of association tests determined by logistic regression analysis with penetrance for genotype with the lowest risk of 0.01 and odds ratio increments of 0.2. The sample size was 1000 for both cases and controls. The penetrance for the genotype with the lowest risk was 0.01, and the odds ratio (r) ranged from 1.1 to 2.0 in increments of 0.2. Red and black circles/lines indicate values for risk allele frequencies shown in red and black, respectively. (TIFF 570 kb)