13045_2020_1029_MOESM3_ESM.tif (545.86 kB)
Download file

Additional file 3 of STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib

Download (545.86 kB)
posted on 15.01.2021, 04:26 by Yahui Zheng, Chong Huang, Lu Lu, Kangkang Yu, Jing Zhao, Mingquan Chen, Lu Liu, Qingfeng Sun, Zhifei Lin, Jianming Zheng, Jinhong Chen, Jubo Zhang
Additional file 3: Figure S1. STOML2 expression is upregulated in HCC tissues and predicts a poor prognosis. (A) The mRNA expression level of STOML2 in HCC tissues (T, n=369) compared with the normal liver tissues (N, n=50) by the GEPIA database. (B-C) Patients with high STOML2 expression have poorer overall survival and disease free survival compared with patients with low STOML2 expression based on the RNA sequencing expression data (group cutoff in 28%/72%) from the TCGA project. *P<0.05. TPM transcripts per million, LIHC Liver hepatocellular carcinoma, HR hazard ratio.


National Natural Science Foundation of China (CN) National Natural Science Foundation of China Natural Science Foundation of Shanghai Zhejiang Province Public Welfare Technology Application Research Project National Key Scientific Instrument and Equipment Development Projects of China