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Additional file 2 of DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations

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posted on 2020-02-01, 04:44 authored by Byung Kim, Ye Jeong, Margaret Wong, Lee Martin
Additional file 2: Figure S2. Western blot for OGG1 proteins levels in human ALS and control motor cortex. Positive control (+control) is human recombinant OGG1.

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National Institutes of Health

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DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations
Acta Neuropathologica CommunicationsActa Neuropathologica Communications

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ApoptosisATMMotor cortexMotor neuronDNA N-glycosylaseBase excision repairp53

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