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Additional file 2 of C3aR costimulation enhances the antitumor efficacy of CAR-T cell therapy through Th17 expansion and memory T cell induction

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posted on 23.05.2022, 03:29 by Peilong Lai, Xiaomei Chen, Yulian Wang, Jinghua Wang, Yuchen Zhang, Suxia Geng, Peng Li, Xin Du, Jianyu Weng, Duanqing Pei
Additional file 2: Fig. S2. The expression of PD-1 was reduced in the 19-BB-ζ-C3aR CAR-T cells. The expression of PD-1 on T cell was determined by flow cytometry. The results showed that BB-ζ-C3aR CAR-T cells presented lower expression of PD-1 compared with mock T or BB-ζ CAR-T cells. *p ≤ 0.05.

Funding

National Natural Science Foundation of China NSFC Incubation Project of Guangdong Provincial People's Hospital National Key Research and Development Program of China High-level Hospital Construction Project of Guangdong Provincial People's Hospital Basic and Applied Basic Research Foundation of Guangdong Province

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