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Additional file 17: Figure S13. of Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

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posted on 01.09.2015, 05:00 by Philip Ruzycki, Nicholas Tran, Alexander Kolesnikov, Vladimir Kefalov, Shiming Chen
E168d2/+ photoreceptor degeneration is light-independent. Retinal morphology of E168d2/+ mice raised under 12 h light–dark cycle (normal light) or constant darkness (dark-reared) for 3 or 6 months. Note that the dark rearing did not improve ONL thinning in the mutant retina. GCL ganglion cell layer, INL inner nuclear layer, IPL inner plexiform layer, OS outer segment, ONL outer nuclear layer, OPL outer plexiform layer. Scale bar = 50 μM. (TIFF 3603 kb)


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