pone.0215250.g002.tif (4.8 MB)

Activation of TLR-connected signaling pathways in response to cervical irradiation.

Download (4.8 MB)
posted on 18.04.2019 by Marie Francoise Mukanyangezi, Lucie Podmolíková, Wurood Al Hydad, Gunnar Tobin, Daniel Giglio

A) Representative microphotographs immunostained for MyD88 (green), TRIF (green) and DAPI-stained nuclei (blue) of control and irradiated cervices (days 1–14 post-irradiation). E indicates epithelium, Subm indicates submucosa and SM indicates smooth muscle. Horizontal bars indicate 200 μm. B) Western blot analysis of MyD88, TRIF and NF-κB expression in control and irradiated cervices (n = 6). ** indicates p<0.01 between TRIF expression in control and irradiated cervices at day 3 post-irradiation. Vertical bars indicate S.E.M.