Fig 8.tif (1.49 MB)
A comparison between expression of co-deregulated microRNAs in recurrent vs. non-recurrent PCa samples.
figureposted on 2017-06-26, 17:40 authored by Elnaz Pashaei, Elham Pashaei, Maryam Ahmady, Mustafa Ozen, Nizamettin Aydin
Those miRNAs that were selected for analysis are depicted above the box plots (Table 3). Lines within the boxes indicate median values; whiskers—min and max for miRNA values. BCR+/ -, biochemical disease recurrence status (positive, negative).
network-based analysisco-deregulated miRNA genesgene ontology enrichmentRPMYCtumor suppressorsmiRNA expression profiles-361-5P-125ATCFPCa researchSeveral miRNA microarray studiesR version 3.3.1. Results Meta-analysis-28-5PCTNNB 1MAX-199AP-value approaches-324-5PmiRNA expression datasetsprognostic significanceprostate cancer recurrencerecurrence PCatarget genesdownregulated miRNA genesprostatectomy Background Prostate cancernon-recurrent PCa samplescolorectal cancerbreast cancer-301Bhepatocellular carcinomasupregulated miRNA genestumor growthhub proteinSREBF 1BCRco-deregulated miRNAs-449B-449AKEGGmiRNA datasetsDE miRNAspathway analysisDE miRNA genes-133A-133Btumor recurrencemiR -939PCa initiationadaptive weightPCa samplescancer typesCYP 26AmiR -98PPI hub proteins analysiscancer pathwaysserum prostate-specific antigen levels