A) Distribution of transcription factor binding motifs relative to differentially accessible ATAC-seq peak summits.

<p>B) Distribution of the number of motifs per peak across ATAC-seq centric clusters. C) Identification of motifs that are associated with specific ATAC-seq clusters demonstrates shared motifs among clusters changing in the same direction with developmental timing (Clusters 1 and 2 or Clusters 3 and 4) but little overlap in those changing in opposite directions (Clusters 3 and 4 compared with Clusters 1, 2, and 5). D) Enrichment of transcription factor binding motifs within the promoter regions of distal peak target genes.</p> <p>(TIF)</p>