FIGURE 2. Har is HOSCN reductase in S. sanguinis. (A) the har-yumC operon, (B) the HOSCN reductase mechanism of Har involving the oxidation of NADH to NAD+ and reduction of HOSCN to SCN- and water, and (C) HOSCN reductase activity of cell lysates expressed as a rate of NADH consumption. Asterisks represent statistical significance between + HOSCN conditions, **** = p<0.0001).
Funding
Molecular Mechanisms of Bacterial Stress Response Relevant to Host-Microbe Interactions