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miRNA host gene expression in gliomas.

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posted on 31.05.2011, 00:09 by Elodie Lages, Audrey Guttin, Michèle El Atifi, Claire Ramus, Hélène Ipas, Isabelle Dupré, Delphine Rolland, Caroline Salon, Catherine Godfraind, Florence deFraipont, Mehdi Dhobb, Laurent Pelletier, Didier Wion, Emmanuel Gay, François Berger, Jean-Paul Issartel

Host gene expression levels in gliomas were assessed by Affymetrix genechip hybridisation and normalized to the expression levels in control brain tissue. The expression levels of the mature miRNAs measured by real-time PCR (Table 1) are reported.

*ratios below 0.33 are in italics.

†ratios above 3 are in boldface.

‡miRNA loci corresponding to miRNAs that showed coexpression with their host genes in normal tissue as reported [13] are underlined.

§The 17 reported genes and transcribed regions host 19 different miRNA loci that code for 15 mature miRNAs.


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