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VapC1 mutations isolated in this study.

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posted on 2014-11-12, 04:48 authored by Brooke Hamilton, Alexander Manzella, Karyn Schmidt, Victoria DiMarco, J. Scott Butler

VapC1 mutations isolated in this study.

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Analysis of Non-Typeable Haemophilous influenzae VapC1 Mutations Reveals Structural Features Required for Toxicity and Flexibility in the Active Site
PLOS ONEPLOS ONE

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  • Biological Sciences

Keywords

toxin proteinpersister formationVapBC TA pairsVapC proteinssite motifVapB antitoxinVapC 1 toxicityantibiotic challengetype II TA systemsbacteriaVapC 1 mutantsActive Site BacteriaVapC toxinsVapC ribonuclease toxinantitoxin VapB 1 counteractsfunctionchemical featuresdormancy mechanismsVapC 1Structural Featuresvivopersister cellspredator cellsenergy utilizationPhylogenetic comparisonsVapBC gene pairsside chainsgene pairs

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