The results of a checkerboard assay using Ag NPs and cefmetazole combinations against drug-resistant N. gonorrhoeae clinical isolates.
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posted on 2013-05-21, 10:28 authored by Lan-Hui Li, Muh-Yong Yen, Chao-Chi Ho, Ping Wu, Chien-Chun Wang, Pawan Kumar Maurya, Pai-Shan Chen, Wei Chen, Wan-Yu Hsieh, Huei-Wen Chena
FICi values above 2.0 indicate antagonistic effects, values between 0.5 and 2.0 indicate additive effects, and values lower than 0.5 indicate synergistic effects.
bResistant status was determined using the disc diffusion method. The following abbreviations are used: penicillin (P), cefixime (CFM), cefpodoxime (CPD), ciprofloxacin (CIP), cefmetazole (CMZ), and tetracycline (TE).
cAg NPs with a diameter of 120 nm were used in assays with clinical isolates.
dNot determined, as ATCC 49226 is sensitive to cefmetazole.
