Summary of gene expression for P19 cells treated + and − RA, P19[Gli2] cells treated - RA, and P19[Gli/EnR] cells treated + RA.
“++” means high upregulation as a result of overexpression, “+” means upregulation, “+/−” means no change, and “−” means downregulation of gene expression as compared to day 0. “N/A” means not applicable. For P19[Gli2] and P19[Gli/EnR] cell lines gene expression was compared to their respective control cell lines.
*Expression of Nanog was downregulated only in undifferentiated P19[Gli/EnR] cells;#
Voronova and Skerjanc, unpublished observations.