Results from linear regression analyses of differences in levels of biomarkers between patients with MS/CIS and SC.

Table 6 shows the results of linear regression analyses on parameters identified in the previous correlation analysis. The regression analyses were performed on log transformed data and if the parameter was correlated to age and/or gender in the correlation analysis these were included in the linear regression. Fold differences in geometric means (GM) and CIs are shown for RRMS, PPMS, and CIS compared with the SC group. The level of significance is shown by the p-value and * marks a significant difference between groups. Abbreviations: RRMS (relapsing-remitting MS), PPMS (primary-progressive MS), CIS (clinically isolated syndrome), SC (symptomatic controls), n (number of persons), CSF (cerebrospinal fluid), CI (confidence interval) NfL (neurofilament light polypeptide), NEO (neopterin), OPN (osteopontin). The data on sCD163 have previously been presented in [18].

Results from linear regression analyses of differences in levels of biomarkers between patients with MS/CIS and SC.