(Results) Bechterevo questionnaire responses - Results.csv

Exploring the Efficacy of Non-Invasive Vagus Nerve Stimulation for Pain Management in Bechterew Disease

Bechterew disease, also known as ankylosing spondylitis, is a chronic inflammatory condition affecting the spine and sacroiliac joints, causing pain, stiffness, and reduced mobility. This study aimed to explore the potential benefits of non-invasive vagus nerve stimulation (nVNS) for pain management in Bechterew disease patients. nVNS is a method that involves electrical stimulation of the vagus nerve through the skin, without the need for surgical implantation. Existing research suggests that nVNS may be effective in reducing pain and inflammation in various conditions.

In this study, participants followed a clinical trial test protocol using the Pulsetto device for nVNS, with 20-minute sessions twice daily. The effectiveness of the treatment was assessed through a daily quiz addressing pain intensity, spinal stiffness, range of motion, sleep quality, and mood. Results demonstrated a significant improvement in joint pain, spinal stiffness, and sleep quality for a majority of participants, while also revealing an overall positive effect on well-being and mood.

Despite these promising results, there are potential risks, challenges, and limitations associated with nVNS, such as possible side effects, varying individual responses, and the need for further optimization of stimulation parameters. Future research directions should focus on optimising nVNS parameters, exploring long-term effects, and assessing the treatment's effectiveness in larger, more diverse patient populations to better understand and optimise its application in Bechterew disease patients.