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Published studies on the frequency of the MSI or MMR-defective phenotype in Pancreatic Ductal Adenocarcinoma.

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posted on 2013-02-19, 22:58 authored by Luigi Laghi, Stefania Beghelli, Antonino Spinelli, Paolo Bianchi, Gianluca Basso, Giuseppe Di Caro, Anna Brecht, Giuseppe Celesti, Giona Turri, Samantha Bersani, Guido Schumacher, Christoph Röcken, Ilona Gräntzdörffer, Massimo Roncalli, Alessandro Zerbi, Peter Neuhaus, Claudio Bassi, Marco Montorsi, Aldo Scarpa, Alberto Malesci
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Tumor specimens passed through xeno-transplantation of PDAC, unspecified whether consecutively collected.

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By genomic DNA analysis for mutations.

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Medullary cancers selected out of 450 randomly chosen PDAC.

“One patient with positive Bethesda criteria but negative hMLH1 mutational analysis.

°3 PDAC arising in LS patients added to a series of 100 patients, unspecified whether consecutive.

Long survivors (≥3 years) selected out of 373 PDAC patients.

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