Number and percent of live poultry market workers and non-poultry worker controls whose serum tested positive for neutralizing antibody against H9 viruses by age.a
Individuals were stratified by age to control for prior exposure to human influenza viruses. In 2001, individuals born in or before 1968 were ≥33 years of age and may have experienced infection with H2N2 and H3N2 viruses while individuals born after 1968 were <33 years of age would not have been exposed to H2N2 viruses.
bNon-adsorbed sera were considered to be preliminarily positive for antibody to an H9 virus if a titer of ≥40 was obtained in two independent assays and tested positive by Western immunoblotting for reactivity with purified recombinant H9 HA.
cSera were adsorbed with human influenza viruses depending on the age of the individual. Sera from individuals <33 years of age were adsorbed with the contemporary human H3N2 virus A/Panama/2007/99; sera from individuals ≥33 years of age were adsorbed with the H2N7 reassortant virus.
dH9N7 virus is a reassortant possessing the hemagglutinin (HA) of A/Chicken/Hong Kong/G9/1997 virus (H9N2) and the neuraminidase (NA) from A/Equine/Prague/1/56 (H7N7) virus.
*p = 0.7710 Fischer's Exact Text.
**p = 1.000 Fischer's Exact Text.