posted on 2015-10-14, 04:12authored byMalgorzata Kluba, Yves Engelborghs, Johan Hofkens, Hideaki Mizuno
<p><sup>a</sup> F stands for the phosphodeficient mutation (phenylalanine substitution).</p><p><sup>b</sup> The strength of negative feedback scaled from as strong as for the EGFR<sup>wt</sup> (+ +) to none (—).</p><p><sup>c, d</sup> Minimum (D<sub>min</sub>) and maximum (D<sub>max</sub>) level of the diffusion coefficient.</p><p><sup>e</sup> The diffusion coefficient averaged over the whole measurement time after EGF addition (D<sub>avg</sub>).</p><p><sup>f</sup> Not determinable.</p><p>Mutational study of the EGFR feedback monomerization at the PLCγ binding sites.</p>