Table_2.xls (9.5 kB)
Download file

Modelling of drug action.

Download (0 kB)
dataset
posted on 22.04.2011, 00:41 authored by Rolf Burghaus, Katrin Coboeken, Thomas Gaub, Lars Kuepfer, Anke Sensse, Hans-Ulrich Siegmund, Wolfgang Weiss, Wolfgang Mueck, Joerg Lippert

Va, IIa, IXa, Xa and XIa denote activated coagulation factors. ATIII, antithrombin; BAY59-7939, rivaroxaban; fu, fraction unbound; Hep, heparin (here parameterized as enoxaparin); on, kon, association rate constant; mIIa, meizothrombin; Tm, thrombomodulin; Xim, ximelagatran active metabolite (melagatran).

History