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Measurement of serum anti-GLA antibodies in Fabry patients received ERT and their phenotype and genotype.

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posted on 2015-06-17, 04:01 authored by Sachie Nakano, Takahiro Tsukimura, Tadayasu Togawa, Toya Ohashi, Masahisa Kobayashi, Katsuyoshi Takayama, Yukuharu Kobayashi, Hiroshi Abiko, Masatsugu Satou, Tohru Nakahata, David G. Warnock, Hitoshi Sakuraba, Futoshi Shibasaki

1)Aga-A; agalsidase alpha

2)Aga-B; agalsidase beta

3)IC; immunochromatography

4)OD; optical density at 450nm

5)Score: 8 scale-values of line density by visual measurement

6)ERT; enzyme replacement therapy

7)NA; not available

8)WT: wild type. Each serum was diluted 100 folds and 5 folds with healthy control serum before ELISA and IC, respectively.

8)Cont: average values of healthy control (Refer to S1 Table).

Measurement of serum anti-GLA antibodies in Fabry patients received ERT and their phenotype and genotype.

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