Mean values of MNPCE frequency and PCE/NCE ratio after simultaneous treatment with cyclophosphamide and the neolignan analogue 2-(4-nitrophenoxy)-1phenylethanone (4NF) in mice for antigenotoxic and anticytotoxic evaluation.
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posted on 2015-11-10, 03:58 authored by Alex Lucas Hanusch, Guilherme Roberto de Oliveira, Simone Maria Teixeira de Sabóia-Morais, Rafael Cosme Machado, Murilo Machado dos Anjos, Lee Chen ChenValues expressed as mean ± standard deviation. DMSO, dimethylsulfoxide; CP, cyclophosphamide (50 mg/kg), nc, negative control; pc, positive control.
* p < 0.05
** p < 0.01
*** p < 0.001 compared to the positive control.
Mean values of MNPCE frequency and PCE/NCE ratio after simultaneous treatment with cyclophosphamide and the neolignan analogue 2-(4-nitrophenoxy)-1phenylethanone (4NF) in mice for antigenotoxic and anticytotoxic evaluation.
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Genetic toxicology evaluationgenotoxic actionrisk assessmentphenylpropanoid unitsscreening testsProtective Effecttumor cellsneolignan analogue 4 NFDNA Damage Neolignansmouse bone marrow micronucleus testgenotoxic activitychemical structuresanticytotoxic activitiescytotoxicitymouse bone marrowDNA damageSeveral compoundsneolignan analoguecomet assaycytotoxicity evaluation
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