Locus description and somatic mutational properties of three highly mutable 3′UTR microsatellites.

Locus information and overall mutation prevalence describes the genetic attributes and mutation status in MSI-H colon tumors for microsatellites located within the 3′UTRs of RB1CC1, NUAK1, and RTF1.

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PhastCons score: Mean and standard deviation of basewise microsatellite sequence conservation score among 31 placental mammals. The value closer to 1 indicates a high conservation level, and a large standard deviation indicates a change in conservation pattern within the microsatellite.

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Flanking miR binding sites: Putative miR binding sites predicted by TargetScan and miRanda scripts within 200 bases of the 3′ or 5′ flanking regions of the corresponding microsatellite.

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Flanking ARE motifs: presence of AU-rich elements within the 3′UTR, according to the Integrated ARED database.