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Isoquinolinone-induced inhibition of cAMP production in MT1-CHO and MT2-CHO cells.

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posted on 05.12.2014, 02:54 by Yueqing Hu, King H. Chan, Xixin He, Maurice K. C. Ho, Yung H. Wong

The pIC50 and %Inhmax were mean ± SEM of 2 trials done in duplicates. The corresponding IC50 values were calculated using the mean pIC50 values.

a

%Inhmax – Maximal percentage inhibition of the forskolin-elevated cAMP level.

b

NSR – no significant response for up to 10 µM of tested compounds in the assay buffer.

c

Extrapolated %Inhmax from non-linear regression.

Isoquinolinone-induced inhibition of cAMP production in MT1-CHO and MT2-CHO cells.

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