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Genital soluble HLA-G levels in HIV-1-uninfected CSWs, HIV-1-infected CSWs, and HIV-1- uninfected non-CSW women according to the HLA-G gene polymorphism.

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posted on 23.09.2011, 00:30 by Valérie Thibodeau, Julie Lajoie, Annie-Claude Labbé, Marcel D. Zannou, Keith R. Fowke, Michel Alary, Johanne Poudrier, Michel Roger

CSW, commercial sex worker; HIV-1, human immunodeficiency virus type 1; I, insertion,

N, number of participants; NS, nonsignificant; SD, standard deviation; SNP, single nucleotide polymorphism; UTR, untranslated region.

Data are mean (SD).

a

P-values for the comparison between all groups were calculated with one-way analysis of variance test.

b

P-values were calculated with Mann-Whitney U test.

c

Presence of the allele in the homozygous or heterozygous states.

d

P = 0.051 for the comparison between HIV-1-uninfected CSWs and HIV-1-infected CSWs, P = 0.153 for the comparison between HIV-1-uninfected CSWs and HIV-1-uninfected non-CSWs and P = 0.002 for the comparison between HIV-1-infected CSWs and HIV-1-uninfected non-CSWs as determined by Mann-Whitney U test.

e

Presence of the variants in the homozygous state.

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