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Generalized linear models for the association of prenatal socioeconomic adversity and HSD11B2 methylation.

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posted on 2013-09-05, 01:56 authored by Allison A. Appleton, David A. Armstrong, Corina Lesseur, Joyce Lee, James F. Padbury, Barry M. Lester, Carmen J. Marsit

Note: Each socioeconomic factor was modeled as the independent variable associated with HSD11B2 methylation extent as the dependent variable. Beta coefficents represent percent change in methylation per unit difference in socioeconomic adversity. Adjusted models control for maternal age, pre-pregnancy BMI, race, infant sex and birth weight percentile. n = 444; additional exclusions were made for poverty and cumulative risk score variables (n = 403).

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p<0.10, *p<0.05, **p<0.01.

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