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Flt3L induced changes in splenic and nodal lymphocyte populations

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posted on 21.01.2013, 16:07 by Mattias N. D. Svensson, Sofia E. M. Andersson, Malin C. Erlandsson, Ing-Marie Jonsson, Anna-Karin H. Ekwall, Karin M. E. Andersson, Anders Nilsson, Li Bian, Mikael Brisslert, Maria I. Bokarewa

during mBSA arthritis.A) Frequency of CD3+, CD19+ and TFH (within the CD4+ population) cells in the spleen and draining lymph nodes at day 28. B) Proliferative response of isolated splenocytes following in vitro stimulation with mBSA (25 μg/ml), LPS (10 μg/ml) or anti-CD3 (1 μg/ml). Results are presented as fold increase compared to non-stimulated cells. Data are presented as mean ± SEM and statistical significance was assessed using unpaired t-test. *P<.05, **P<.01.

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