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Fine mapping association results of NRG1 SNPs using logistic regression on MACH-imputed allelic dosage

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posted on 20.01.2011, 01:31 by Clara Sze-Man Tang, Wai-Kiu Tang, Man-Ting So, Xiao-Ping Miao, Brian Man-Chun Leung, Benjamin Hon-Kei Yip, Thomas Yuk-Yu Leon, Elly Sau-Wai Ngan, Vincent Chi-Hang Lui, Yan Chen, Ivy Hau-Yee Chan, Patrick Ho-Yu Chung, Xue-Lai Liu, Xuan-Zhao Wu, Kenneth Kak-Yuen Wong, Pak-Chung Sham, Stacey S. Cherny, Paul Kwong-Hang Tam, Maria-Mercè Garcia-Barceló

Only SNPs with P-value lower than either or both of the 2 previously implicated SNPs (rs16879552 and rs7835688) are shown;

a

: minor allele frequency; underlined: SNPs found associated in the previously reported GWAS.

b

: frequencies reported for imputed alleles (except for rs3802159 and rs7834206);

c

: minor and major alleles in patients and controls combined; in bold genotyped SNP with the lowest p association value.

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