Emodin and coleon AL inhibit endothelial cell proliferation in vitro.
dataset
posted on 2013-02-20, 20:29 authored by Alexander D. Crawford, Sandra Liekens, Appolinary R. Kamuhabwa, Jan Maes, Sebastian Munck, Roger Busson, Jef Rozenski, Camila V. Esguerra, Peter A. M. de WitteIC50 values (± SD) for emodin and coleon A lactone are shown for the inhibition of proliferation of both bovine aortic endothelial cells (BAEC) and mouse aortic endothelial cells (MAEC). For comparison, effects of 3 other anti-angiogenic compounds are shown (wortmannin, LY294002, and SU5416).
