Table_2.xls (17.5 kB)

CpG sites with differential methylation between acute lymphoblastic leukemia cells and remission cells.

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posted on 06.04.2012, 02:03 by Jessica Nordlund, Lili Milani, Anders Lundmark, Gudmar Lönnerholm, Ann-Christine Syvänen
a

Gene symbol according to the HUGO Gene Nomenclature Committee (http://www.genenames.org/);

*

indicates genes selected from the literature;DBC1 [24]; RUNDC3B [25].

b

Chromosome number and coordinate of the CpG site (Human genome build 36).

c

Distance from the transcription start site (TSS); −, upstream from the TSS; +, downstream from the TSS.

d

Median difference in beta-value between ALL patients at diagnosis and remission for paired samples (ALL-remission).

e

Number of ALL-remission pairs with Δβ-values larger than 0.30.

f

Adjusted Wilcoxon Signed-Rank P-values corrected for multiple testing with the Benjamini Hochberg approach.

g

Genes up (+) or down (−) regulated in ALL cells compared to controls according to published datasets [16], [17], n.c. = no change.

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