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Conservation of imprints in human and mouse

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posted on 2013-02-21, 00:48 authored by Jennifer M. Frost, Gudrun E. Moore

Many genes in the mouse are imprinted specifically in the placenta. A lack of conservation exists between the human and the mouse, where these placental-specific genes are not imprinted at all in the human. Of these genes, all except Air and Tsix are maternally expressed, and except Igf2r, Air and Ascl2, are all confined either in their expression or their imprinting to the placenta [25], [46], [52], [104].


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