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Biomarkers in the Ten Most Specific and Sensitive 7-Marker Models Using a Noise Parameter of 1.0*.

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posted on 2009-02-25, 02:10 authored by Suraj D. Amonkar, Greg P. Bertenshaw, Tzong-Hao Chen, Katharine J. Bergstrom, Jinghua Zhao, Partha Seshaiah, Ping Yip, Brian C. Mansfield

A comparable list was generated for a noise parameter of 3.0; x, biomarker used in a given model.


All models were required to contain an invariant core of the three most robust and informative analytes, namely CA-125, C-reactive protein and EGF-R. CA, cancer antigen; CRP, C-reactive protein; EGF-R, soluble epidermal growth factor receptor; SAP, serum amyloid P; Apo, apolipoprotein; MIP-1α, macrophage inhibitory protein 1α; EN-RAGE, Protein S100-A12; CK-MB, creatine kinase-MB; vWF, von Willebrand Factor; GH, growth hormone; MPO, myeloperoxidase; VCAM-1, vascular cell adhesion molecule 1.


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