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Azole resistance PCR results of 25 investigated blood (PB = peripheral blood), 120 BAL, 17 tissue biopsies and 19 CSF samples.

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posted on 2014-07-29, 03:04 authored by Birgit Spiess, Patricia Postina, Mark Reinwald, Oliver A. Cornely, Axel Hamprecht, Martin Hoenigl, Cornelia Lass-Flörl, Peter-Michael Rath, Jörg Steinmann, Thomas Miethke, Melchior Lauten, Silke Will, Natalia Merker, Wolf-Karsten Hofmann, Dieter Buchheidt

106 samples including all blood samples were PCR negative in the most sensitive L98H PCR assay. Investigation of 32 samples revealed positive PCR results in all three PCR assays and showed three times the L98H mutation, two times in combination with the TR34. n, number of clinical samples.

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Incidence of Cyp51 A Key Mutations in Aspergillus fumigatus—A Study on Primary Clinical Samples of Immunocompromised Patients in the Period of 1995–2013
PLOS ONEPLOS ONE

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Diagnostic medicinehematologyInfectious diseasespcr25investigated12017biopsies19csf

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