Whole-body PBPK Model Rate Equations.
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posted on 2016-09-16, 17:35 authored by James P. Sluka, Xiao Fu, Maciej Swat, Julio M. Belmonte, Alin Cosmanescu, Sherry G. Clendenon, John F. Wambaugh, James A. GlazierWhole-body PBPK Model Rate Equations.
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acetaminophen overdoseblood flow modelingphase II metabolismliver toxicityexchange modelssilico modeling frameworkmodel codeglucuronate metabolitesSystems Biology Markup Languagebody levelpurpose pharmacokinetic modelsub-cellular scalesmodeling modalitiesLiver-Centric Multiscale Modeling FrameworkSBMLacetaminophen pharmacologypopulation variationvivo datasub-modelPBPKmodeling frameworkparameter sensitivity studiesmodeling approachbody uptakeacetaminophen uptakeliver transportsub-cellular levelpairwise interaction
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